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Archived Comments for: Orphan SelD proteins and selenium-dependent molybdenum hydroxylases

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  1. Acknowledging an earlier observation of orphan SelD

    Daniel Haft, J. Craig Venter Institute

    4 March 2008

    Just after publication of our manuscript, we came across the following reference: Zhang Y, Romero H, Salinas G, Gladyshev VN., Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues. Genome Biol. 2006;7(10):R94. Epub 2006 Oct 20. We launched our study from the observation that SelD proteins explained by neither selenocysteine nor selenouridine pathways might imply a third SelD-dependent trait. The orphan status of SelD in Enterococcus faecalis and Haloarcula marismortui and possibility of SelD-dependence for selenium-dependent molybdenum hydroxylases were raised previously by Zhang, et al., and should have been cited as background to this paper. We regret having been unaware of this earlier observation.

    Competing interests

    none

  2. Acknowledged reference

    Andrea Melendez-Acosta, BioMed Central

    10 March 2008

    To access the above referenced article please click here.

    Competing interests

    None

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