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Figure 5 | Biology Direct

Figure 5

From: Retrospective analysis of protein kinase C-beta (PKC-β) expression in lymphoid malignancies and its association with survival in diffuse large B-cell lymphomas

Figure 5

Relationship between PKC-β gene expression as an outcome predictor and the international prognostic index (IPI). The IPI classifies patients into 3 risk groups: low-risk, defined by an IPI score of 0–1; intermediate-risk, defined by an IPI score of 2–3; and high-risk, defined by an IPI score of 4–5. IPI scores were unknown for 18 patients. A. Number of patients represented in each PKC-β defined quartile for the IPI low-, intermediate-, and high-risk subgroups. B. Kaplan-Meier plots of overall survival for IPI low-, intermediate-, and high-risk subgroups, stratified according to the quartile of PKC-β expression. Quartile 1 was combined with quartile 2 and quartile 3 was combined with quartile 4 to allow for more robust comparisons. Higher quartiles represent groups with higher PKC-β expression.

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