Evolution of glyoxylate cycle enzymes in Metazoa: evidence of multiple horizontal transfer events and pseudogene formation

Table 2 Pairwise comparisons of malate synthase genes in Coelomata genomes.

	Anopheles gambiae	Aedes aegypti	Bombyx mori	Strongylocentrotus purpuratus	Danio rerio	Takifugu rubripes	Tetraodon nigroviridis	Xenopus tropicalis	Monodelphis domestica
Anopheles gambiae		65.2561	66.8261	66.3264	65.3852	21.7031	59.0776	62.9706	65.6821
Aedes aegypti	0.1874		64.6634	66.2250	66.4475	63.7981	65.8231	12.0822	66.8287
Bombyx mori	0.4153	0.4429		64.8519	7.2214	66.0626	66.5992	66.4243	65.9305
Strongylocentrotus purpuratus	0.4654	0.4957	0.5145		7.0848	27.4334	18.0603	56.6819	64.4132
Danio rerio	0.4748	0.4742	0.5009	0.3354		3.6424	6.9404	12.1555	12.9374
Takifugu rubripes	0.4522	0.4805	0.4817	0.3317	0.1844		0.3413	12.8377	37.2786
Tetraodon nigroviridis	0.4414	0.4585	0.4728	0.3298	0.1919	0.0441		36.8792	19.8208
Xenopus tropicalis	0.4877	0.5024	0.4543	0.3374	0.2440	0.2583	0.2530		3.5119
Monodelphis domestica	0.4395	0.4348	0.4682	0.3013	0.2222	0.2211	0.2189	0.1533

The lower half of the table shows the rates of evolution in nonsynonymous sites, and the upper half shows the rates of evolution in synonymous sites. Most of the synonymous evolution rates were at the saturation levels. However, in each case, the estimated nonsynonymous substitution rate was significantly lower than the corresponding synonymous rate, which is indicative of purifying selection at the amino acid sequence level.

ISSN: 1745-6150