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Table 4 Frequency of T lymphocytes expressing CD69 and CD25 activation markers in spleen and peritoneal ascitic fluid of C57BL/6 mice transplanted with #40a MM cells

From: Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

Cells

Spleen

Ascites

Control

Bor

p value

Control

Bor

p value

CD4+CD69+

11.4 ± 2.1

10.0 ± 1.3

ns

13.1 ± 9.0

34.2 ± 3.9

p ≤ 0.01

CD8+CD69+

6.1 ± 1.6

5.9 ± 1.0

ns

21.8 ± 2.2

25.1 ± 8.9

ns

CD4+CD25+

9.8 ± 2.2

9.8 ± 1.4

ns

14.5 ± 7.2

32.1 ± 7.8

p ≤ 0.01

CD8+CD25+

2.3 ± 0.8

1.7 ± 0.2

ns

2.4 ± 1.3

6.9 ± 2.7

p ≤ 0.01

  1. ns not significant
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Biology Direct

ISSN: 1745-6150

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