Fig. 10
From: Identification of a prognostic cuproptosis-related signature in hepatocellular carcinoma
PDXK is related to copper ionophore-induced cell death. A The illustration of cuproptosis induction model. B The expression level change of cuproptosis-related genes (PDXK, HPN, SLC25A28, RNFT1 and CLEC3B) in indicated groups were presented by qPCR. C, D HCC cells transfected with PDXK specific siRNA or scramble control were treated with the indicated concentrations of elesclomol-CuCl2 and cell viability was evaluated by MTT assay after 72 h. ns, not significant, p > 0.05; *p < 0.05; ***p < 0.001. TTM, tetrathiomolybdate