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Fig. 1 | Biology Direct

Fig. 1

From: Lactobacillus rhamnosus GG ameliorates radiation-induced lung fibrosis via lncRNASNHG17/PTBP1/NICD axis modulation

Fig. 1

SNHG17 is a LGG-modulated lncRNA in response to radiation. a A549 cells were divided into 4 groups, control group (Con), treated with LGG group (LGG), 6 Gy radiation group (IR) and LGG treated prior to 6 Gy radiation (LGG + IR). b Up- and down-regulated numbers of lncRNAs in LGG + IR versus IR. c Heatmap of differentially expressed lncRNAs in LGG + IR versus IR. Red presents upregulated lncRNAs and purple presents down-regulated lncRNAs. d Volcano plot of differentially expressed lncRNAs in LGG + IR versus IR. Red presents upregulated lncRNAs and green presents down-regulated lncRNAs. e KEGG analysis the predicted pathway involved by the differential expressed lncRNA within LGG + IR versus IR. Data are means ± SD (standard deviation). N = 3 independent experiments, Student’s two-tailed unpaired t test was used to compare differences between two groups. *p < 0.05

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