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Fig. 6 | Biology Direct

Fig. 6

From: M2 macrophage-derived exosomal miR-193b-3p promotes progression and glutamine uptake of pancreatic cancer by targeting TRIM62

Fig. 6

TRIM62 interacts with c-Myc and induces c-Myc ubiquitination. A Immunoprecipitation was performed, and immunoprecipitants were probed with indicated antibodies. B SW1990 cells transfected with TRIM62 overexpression plasmid were treated with or without MG132 (10 µM), and TRIM62 and c-Myc expressions were evaluated. C SW1990 cells transfected with TRIM62 overexpression plasmid were treated with CHX, and c-Myc levels were measured. D SW1990 cells transfected with TRIM62 overexpression plasmid were immunoprecipitated with c-Myc for ubiquitination analysis. **P < 0.01, ***P < 0.001 versus vector

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