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Fig. 3 | Biology Direct

Fig. 3

From: Long-read assembly of major histocompatibility complex and killer cell immunoglobulin-like receptor genome regions in cynomolgus macaque

Fig. 3

Comparative genomic map of the MHC and KIR region in human, rhesus and cynomolgus macaque. a Comparative genomic map of the protein-coding MHC genes in human (HLA), rhesus macaque (Mamu) and cynomolgus macaque (Mafa). Red and blue boxes indicate MHC class I and class II genes, respectively. Distances between genes are not scaled. b Comparative genomic map of the HLA-B, Mamu-B and Mafa-B regions (contig utg000348l). Distances between genes are not scaled. The table on the right shows the Mafa-B alleles with the highest frequency in our study (frequencies in between brackets). c Comparative genomic map of the KIR genes in human (haplotype A and B), rhesus and cynomolgus macaque (contig utg000460l). Distances between genes are not scaled. Purple represents activating KIR genes, green represents inhibitory KIR genes, pink represents pseudogenes, and KIRID genes are shown in yellow. Due to the high diversity of KIR genes in rhesus macaques, and the variable copy number of KIR genes per haplotype, the specific names of the KIR genes in rhesus macaques are not indicated in the figure

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