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Fig. 6 | Biology Direct

Fig. 6

From: p53 regulates expression of nuclear envelope components in cancer cells

Fig. 6

Nuclear component expression is a prognostic factor in human cancer. A RNA expression of the selected members of NPC in PDAC samples stratified by tumour weight (≤ 3.5 cm n = 80 patients, or > 3.5 cm n = 58 patients); dot plot data (z-score) are presented by mean (red line) ± SEM; source data: cBioportal [8], and Cao et al. [7], *p-value < 0.05; **p-value < 0.01. B Disease free survival analysis of pancreatic cancer patients stratified by NUP54 mRNA levels; source GEPIA2 [43], (high level cohort = 89 patients; low level cohort = 89 patients). C RNA expression analysis for the selected members of NL and NPC according to TP53 status, wild type (Wt) and mutant (Mut), in hepatocellular carcinoma (HCC); data are expressed as log RNAseq V2 RSEM by box and whiskers plot; source TCGA, cBioportal [8]; n = 366 patients; **p-value < 0.01; ****p-value < 0.0001. D Overall survival of hepatocellular carcinoma (HCC) patients stratified for high or low mRNA levels of selected genes; source GEPIA2 [43]

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