N6-methyladenosine-mediated SH3BP5-AS1 upregulation promotes GEM chemoresistance in pancreatic cancer by activating the Wnt signaling pathway

Table 1 Relationship between SH3BP5-AS1 expression and clinicopathological parameters in 87 PC patients

Variables	All cases	SH3BP5-AS1 expression		P
Variables	All cases	Low (n = 31)	High (n = 56)	P
Age (years)
< 50	40	14	26	0.910
≥ 50	47	17	30
Gender
Male	59	22	37	0.640
Female	28	9	19
Alcohol history
No	41	14	27	0.785
Yes	46	17	29
Smoking
No	37	12	25	0.592
Yes	50	19	31
CEA
Normal	17	9	8	0.097
High	70	22	48
CA199
Normal	26	12	14	0.181
High	61	19	42
Tumor size (cm)
< 4	52	23	29	0.041^*
≥ 4	35	8	27
TNM stage
I-II	31	16	15	0.02^*
III-IV	56	15	41
Lymph node invasion
Absent	61	26	35	0.035^*
Present	26	5	21
Metastasis
No	40	19	21	0.034^*
Yes	47	12	35

ISSN: 1745-6150