Skip to main content
Fig. 3 | Biology Direct

Fig. 3

From: In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials

Fig. 3

Performance analysis of RNA structure prediction of CRISPR repeats with PyMOL align. Heatmap of the means of the RMSD values by superimposition of each predicted crRNA 3-D structure with the ground truth (GT) structure. The RNA 2-D structure prediction programs are shown on the y-axis, and the PDB name of each Cas13 protein is shown on the x-axis, with the RNA 3-D structure program as a RNAComposer and b Rosetta. c Superimposition of the GT structure 6IV8_B predicted by ContextFold and RNAComposer (best), and 6AAY predicted by ContextFold and RNAComposer (worst). d Superimposition of the GT structure 6DTD predicted by RNAstructure and Rosetta (best), and 6IV8_D predicted by RNAstructure and Rosetta (worst). Grey = GT structure; Magenta = predicted structure

Back to article page