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Fig. 7 | Biology Direct

Fig. 7

From: An integrative in-silico analysis discloses a novel molecular subset of colorectal cancer possibly eligible for immune checkpoint immunotherapy

Fig. 7

Example of ICGs differentially expressed in HM, non-HM and HM-like groups. The Box Plots show A ICGs more expressed in HM group versus non-HM, which may (KIR genes) or may not (HLA genes) be significantly more expressed in HM-like vs non-HM tumors; B gene sharing a similar trend of expression between HM and HM-like; C gene specifically more expressed in HM-like group (VTCN1 and BTNL9) or with an opposite trend of expression in HM versus HM-like (CD40LG). The analysis was performed using the multiple comparison of the three subgroups using Wald test and P value was adjusted according to the Benjamini–Hochberg method. Thresholds for FDR < 0.1 and Log2 Fold Change > 0.4 were used to select significant differentially expressed genes

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Biology Direct

ISSN: 1745-6150

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