Table 1 The most common protein families associated with ATP-grasp enzymes
From: Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis
Cluster number | Weighted frequency (%) | Number of occurrences | CDD PSSM | Description |
|---|---|---|---|---|
Cluster 4 | 0.19 | 433 | COG1132 | Double glycine peptidase (C39 family) and RiPP specific ABC transporter |
Cluster 3 | 0.18 | 717 | TIGR04188 | Protein-L-isoaspartate(D-aspartate) O-methyltransferase, RiPPs specific |
Cluster 20 | 0.13 | 185 | TIGR04193 | SPASM domain peptide maturase |
Cluster 16 | 0.09 | 191 | TIGR01843 | Type I secretion membrane fusion protein HlyD-family, macrolide-specific efflux protein, periplasmic |
Cluster 18 | 0.04 | 198 | Â | Uncharacterized membrane protein |
Cluster 23 | 0.03 | 150 | Â | Uncharacterized protein |
Cluster 14 | 0.03 | 85 | pfam13581 | Histidine kinase-like ATPase domain |
Cluster 146 | 0.02 | 40 | Â | Uncharacterized protein, same family as cluster 23 |
Cluster 8 | 0.02 | 68 | pfam13560 | Helix-turn-helix domain, often fused to uncharacterized protein DUF5753 |
Cluster 5 | 0.02 | 84 | Â | TPR-repeats containing protein |
Cluster 9 | 0.02 | 30 | COG1028 | Short chain dehydrogenase |
Cluster 163 | 0.02 | 31 | pfam14905, TIGR04056 | Outer membrane protein beta-barrel family; TonB-linked outer membrane protein, SusC |
Cluster 145 | 0.02 | 40 | TIGR04500 | Peptidyl-prolyl cis–trans isomerase family protein |
Cluster 24 | 0.02 | 50 | pfam00561 | Alpha/beta hydrolase |
Cluster 7 | 0.02 | 25 | pfam00005 | ABC transporter, ATPase binding component |
Cluster 40 | 0.02 | 86 | Â | Uncharacterized membrane protein |
Cluster 11 | 0.02 | 92 | COG0745 | DNA-binding response regulator, OmpR family |
Cluster 6 | 0.01 | 39 | COG1309 | DNA-binding transcriptional regulator, AcrR |