Fig. 6
From: Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis
Predicted precursors and loci organization in ATP-grasp branches 3, 4, 6, 7 and 8. Selected loci organization are shown for each branch. Genes are depicted by block arrows, roughly to scale. Genes are colored according to the homology and the key which is shown at the bottom of the Figure. Cluster number indicated above the arrows is provided for all genes, except those coding for ATP-grasp proteins. Genbank accession and coordinates of the locus and the name of the organism are indicated on the right of each locus schematics. Consensus sequences for clusters of putative precursors are shown below loci schematics for Branch 3, 4 and 6, cluster numbers are indicated on the left. Amino acids highlighted as follows: conserved amino acids that could be involved in formation of ester or amide bonds are highlighted by red, GG-motifs are highlighted by blue, conserved amino acids in putative leader peptides are highlighted by green. Asterisk indicates cluster 75 which is known from previous studies but shown here for comparison because it is associated with Branch 3. Amino acid sequence for putative precursor in the Streptomyces viridosporus T7A locus is shown