Fig. 6
From: LINC00885 promotes cervical cancer progression through sponging miR-3150b-3p and upregulating BAZ2A
LINC00885/miR-3150b-3p/BAZ2A axis regulated cell proliferation and apoptosis in CC. A BAZ2A was silenced by transfection of sh-BZA2A#1/2/3 in HeLa cells as indicated in RT-qPCR and western blot analyses. HeLa cells were transfected with sh-Ctrl, sh-LINC00885#1, sh-LINC00885#1 + miR-3150b-3p inhibitor, or sh-LINC00885#1 + miR-3150b-3p inhibitor + sh-BAZ2A#1 respectively for subsequent assays. B–D CCK-8, EdU and colony formation assays were done to detect proliferation of HeLa cells transfected with indicated plasmids. E–F TUNEL assay and western blot analysis of expression levels of apoptosis-related genes (cleaved and total caspase 3 and caspase 9) were done to determine apoptosis of HeLa cells under different transfection conditions. *P < 0.05, **P < 0.01