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Fig. 5 | Biology Direct

Fig. 5

From: Study on the mechanism of LOXL1-AS1/miR-3614-5p/YY1 signal axis in the malignant phenotype regulation of hepatocellular carcinoma

Fig. 5

LOXL1-AS1 exacerbates the malignant behaviors of HCC cells via miR-3614-5p/YY1. A, B Colony formation assay and EdU assay measured cell proliferation in different groups, specifically, sh/NC, sh/LOXL1-AS1#1, sh/LOXL1-AS1#1 + inhibitor and sh/LOXL1-AS1#1 + pcDNA3.1/YY1. C, D In addition to detection of mitochondrial membrane potential by JC-1 to reflect cell apoptosis, the apoptotic ability of cells was also evaluated via TUNEL assay in different groups. E, F Transwell assays estimated cell migration and invasion in different groups. **P < 0.01

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