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Fig. 4 | Biology Direct

Fig. 4

From: Study on the mechanism of LOXL1-AS1/miR-3614-5p/YY1 signal axis in the malignant phenotype regulation of hepatocellular carcinoma

Fig. 4

YY1 accelerates cell proliferation, migration, invasion but inhibits cell apoptosis in HCC. A YY1 expression in HCC cells transfected with sh/YY1 was tested via qRT-PCR. B Cell proliferation was measured by colony formation assay under the influence of YY1 depletion. C JC-1 assay was utilized to for the detection of mitochondrial membrane potential when YY1 was silenced in cells to reflect the changes of cell apoptosis. D EdU assay estimated the proliferative capacity of sh/YY1-transfetced cells and sh/NC-transfected cells. E TUNEL assay detected cell apoptosis after we silenced YY1 in cells. F, G Transwell assay estimated cell migration and invasion when YY1 was knocked down in cells. **P < 0.01

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