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Fig. 5 | Biology Direct

Fig. 5

From: Circ_0067680 expedites the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through miR-4429/CTNNB1/Wnt/β-catenin pathway

Fig. 5

CTNNB1 is targeted by miR-4429. A CTNNB1 expression was examined after transfection of miR-4429 mimics in hBMSCs by RT-qPCR. B The binding regions between miR-4429 and CTNNB1. C RIP assay displayed the abundance of circ_0067680, miR-4429 and CTNNB1 in Ago2 antibody. D The binding between miR-4429 and CTNNB1 was verified by luciferase reporter assay. E Transfection of miR-4429 inhibitor to reduce miR-4429 expression. F, G The expression of CTNNB1 was examined in the sh-NC group, sh-circ_0067680#1 group and sh-circc_0067680#1 + miR-4429 inhibitor group. **P < 0.01

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Biology Direct

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