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Fig. 2 | Biology Direct

Fig. 2

From: NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network

Fig. 2

Mutant p53 regulates a RCan2 expression via GOF effects. a Oncoprint diagram reports mutational status of RCan2 and NUAK2 in full cohort of TCGA PanCancer Atlas. bd mRNA level of RCan2, NUAK2 and p53 in KPC270 cells following p53 silencing. e ChIP-seq profile of histone post-translational modifications, transcriptional factors binding in the genomic region of mouse RCan2. f ChIP-qPCR for p53 binding on peak 1 and peak 2 in KPC270 cells

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