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Fig. 4 | Biology Direct

Fig. 4

From: Long non-coding RNA SNHG8 enhances triple-negative breast cancer cell proliferation and migration by regulating the miR-335-5p/PYGO2 axis

Fig. 4

SNHG8 promotes the proliferation, migration and EMT of TNBC cells by sponging miR-335-5p. A We adopted RT-qPCR assay to detect miR-335-5p inhibitor transfection efficiency in TNBC cells. B Colony formation assay was conducted to detect the proliferation of TNBC cells transfected with sh/NC, sh/SNHG8#1 or sh/SNHG8#1 + miR-335-5p inhibitor. C Transwell assay was utilized to assess the number of migrated TNBC cells in different treatment groups. D RT-qPCR and western blot assays were used to examine E-cadherin, N-cadherin, Vimentin, MMP2 or MMP7 mRNA and protein levels in TNBC cells of each group. **P < 0.01

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