Fig. 8
in panel a the participation coefficient, P, of each amino acid of wt-Aro is shown, according to the colors code whose numerical value is reported in the left scale. In panel b the distribution of the P values is presented as a function of the sequence position (X-axis) and of the belonging to one of the two clusters (red or green) identified in Fig. 7. <P > is the protein average participation coefficient. The area of the dashed rectangle corresponds to the G-helix residues. In panel c the difference ΔP = Psb– P between the P values of the holo and apo forms is reported. The green color has been attributed to those residues whose P value does not change (ΔP = 0) upon ligand binding