Fig. 6From: Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidenceANS-binding curves of wt-Aro (circles) and mutants R264H (squares) or R264C (triangles) in the presence of saturating concentration of substrate (green) or inhibitor (red). The concentration of all the proteins is 6.4 μM. The solid lines correspond to the best fit obtained for each sample by a chi-squared minimization procedure (see materials and methods)Back to article page