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Table 4 Signal transferability. The number of common variables in top N variables of one cell line in top 200, variables is shown. The last column shows the AUC of a model built for the second cell line, using 100 most informative variables from the first cell line. The cell line used for model building, and AUC of the model are displayed in boldface

From: Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

top N cells

top 200 cells

N=10

N=20

N=50

N=100

N=200

AUC

VCAP

MCF7

0

2

6

19

40

0.58

MCF7

VCAP

4

6

9

19

40

0.56

SKB

MCF7

1

1

7

14

34

0.58

MCF7

SKB

1

4

15

21

34

<0.56

HA1E

MCF7

2

4

10

22

40

0.57

MCF7

HA1E

2

6

12

19

40

<0.56

HEPG2

MCF7

3

4

10

18

30

0.57

MCF7

HEPG2

0

2

9

13

30

<0.56