Fig. 3
From: Prediction and mechanistic analysis of drug-induced liver injury (DILI) based on chemical structure
Distribution of protein feature importance in the best performing RF and SVM models. Proteins significantly enriched in the DILI class are labelled in orange, while all other proteins are colored in blue. Among the proteins with high feature importance are many whose involvement in DILI has been established before, such as AKR1B1, CYP1A2 and MAPK11, and this analysis might give further hints at novel proteins involved in DILI