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Table 1 Summary of multi-omics multi-cohort glioma datasets

From: Computational identification and characterization of glioma candidate biomarkers through multi-omics integrative profiling

Category

Accession number

Source

Omics type

# Samples

# Population country/race

Reference

Discovery

D1-GTEx-E

GTEx

Expression (RNA-Seq)

11,688

mostly white

[39]

D2-GSE83710-P

GSE83710

Protein

133

Japan

[43]

D3-GSE16011-E

GSE16011

Expression (Microarray)

284

Netherlands

[44]

D4-TCGA-V

TCGA

CNV

1018

mostly white

[35]

D4-TCGA-E

TCGA

Expression (RNA-Seq)

607

mostly white

[35]

D4-TCGA-M

TCGA

Methylation (27 K + 450 K)

862

mostly white

[35]

D4-TCGA-M (TMZ treatment)

TCGA

Methylation (27 K + 450 K)

228

 mostly white

[35]

D5-GSE36278-M

GSE36278

Methylation (450 K)

142

Germany

[45]

Validation

V1-GSE4290-E

GSE4290

Expression (Microarray)

180

USA

[46]

V2-GSE50161-E

GSE50161

Expression (Microarray)

47

USA

[47]

V3-GSE59612-E

GSE59612

Expression (RNA-Seq)

92

USA

[48]

V4-GSE111260-E

GSE111260

Expression (Microarray)

70

Norway

–

V5-GSE2223-E

GSE2223

Expression (Microarray)

54

USA

[49, 50]

V6-Ivy GAP-E

Ivy GAP

Expression (RNA-Seq)

122

unknown

[40]

V7-CGGA-E

CGGA

Expression (Microarray)

301

China

[42, 51]

V8-GSE50923-M

GSE50923

Methylation (27 K)

78

USA

[52]

V9-GSE61160-M

GSE61160

Methylation (450 K)

51

Spain

[53]

V10-CGGA-M

CGGA

Methylation (27 K)

159

China

[54]

V11-TCGA-M

TCGA

Methylation (WGBS)

6

white

–

V12-CGGA-E

CGGA

Expression (RNA-Seq)

310

China

[41]

V13-CGGA-E

CGGA

Expression (RNA-Seq)

667

China

–

V14-GSE60274-M

GSE60274

Methylation (450 K)

68

Switzerland

[55]

  1. CGGA Chinese Glioma Genome Atlas, http://www.cgga.org.cn
  2. GEO Gene Expression Omnibus, https://www.ncbi.nlm.nih.gov/geo/
  3. GTEx Genotype-Tissue Expression, https://www.gtexportal.org
  4. TCGA The Cancer Genome Atlas, https://portal.gdc.cancer.gov
  5. Ivy GAP Ivy Glioblastoma Atlas Project, http://glioblastoma.alleninstitute.org