Fig. 1

MDA19 treatment inhibited HCC cell proliferation in a dose- and time-dependent manner. a Hep3B (Left) and HepG2 (Right) cells were treated with a concentration gradient of MDA19 (0, 5, 10, 20, 30, 40, 50, 80, 100, 120 μM) for 48 h and then cell proliferation was detected by CCK8 assay; (b) Hep3B (Left) and HepG2 (Right) cells were treated with MDA19 at 30 μM and 40 μM, respectively. Cell proliferation was detected at 0 h, 24 h, 48 h and 72 h using CCK8 assays; (c) Hep3B and HepG2 cells were treated with MDA19 for 48 h at 30 μM and 40 μM, respectively. Then the clone formation ability of HCC cells was detected. All experiments were performed at 3 times. *P < 0.05