Table 1 Transient protein-protein complexes of known 3-D structure employed for the analysis. For every entry in this dataset, a corresponding PDB entry is observed in the ‘unbound’ for at least one of the two proteins in the complex (details are in Additional file 1: Table S1)
PDB code | Resolution (Ã…) | Complex structure title | Source organism |
|---|---|---|---|
1AY7 | 1.7 | Ribonuclease SA complex with Barstar | Bacillus amyloliquefaciens |
1B0N | 1.9 | SINR/SINI protein complex | Bacillus subtilis |
1F3V | 2 | N-terminal domain of TRADD and the TRAF domain of TRAF2 | Homo sapiens |
1FM0 | 1.45 | Molybdopterin Synthase (MOAD/MOAE) | Escherichia coli |
1G73 | 2 | SMAC bound to XIAP-BIR3 domain | Homo sapiens |
1GL4 | 2 | Nidogen-1 G2/Perlecan IG3 Complex | Mus musculus |
1HX1 | 1.9 | BAG domain in complex with the HSC70 ATPASE domain | Bos taurus |
1JIW | 1.74 | APR-APRin complex | Pseudomonas aeruginosa |
1NRJ | 1.7 | Signal Recognition Particle Receptor Beta-Subunit in Complex with the SRX Domain from the Alpha-Subunit | Saccharomyces cerevisiae |
1O6S | 1.8 | Internalin (Listeria monocytogenes) / E-Cadherin (human) Recognition Complex | Homo sapiens |
1OR7 | 2 | Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA | Escherichia coli |
1PXV | 1.8 | Staphostatin-staphopain complex | Staphylococcus aureus |
1R0R | 1.1 | Protein Inhibitor, OMTKY3, and the Serine Protease, Subtilisin Carlsberg | Bacillus licheniformis |
1T0F | 1.85 | TnsA/TnsC(504–555) complex | Escherichia coli |
1T6G | 1.8 | Triticum aestivum xylanase inhibitor-I in complex with aspergillus niger xylanase-I | Aspergillus niger |
1TA3 | 1.7 | Crystal Structure of xylanase (GH10) in complex with inhibitor (XIP) | Aspergillus nidulans |
1UUZ | 1.8 | IVY:A NEW FAMILY OF PROTEIN | Gallus gallus |
1WQJ | 1.6 | Insulin-Like Growth Factors (IGFs) in complex with IGF Binding Proteins (IGFBPs) | Homo sapiens |
1Z0J | 1.32 | Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5 | Homo sapiens |
1Z5Y | 1.94 | N-Terminal Domain Of The Electron Transfer Catalyst DsbD and The Cytochrome c Biogenesis Protein CcmG | Escherichia coli |
1ZHH | 1.94 | Apo Form of Vibrio Harveyi LUXP Complexed with the Periplasmic Domain of LUXQ | Vibrio harveyi |
1ZLH | 1.7 | Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A | Bos taurus |
2APO | 1.95 | Methanococcus jannaschii Cbf5 Nop10 Complex | Methanocaldococcus jannaschii |
2CIO | 1.5 | Papain complexed with fragments of the Trypanosoma brucei cysteine protease inhibitor ICP. | Carica papaya |
2DFX | 1.9 | Carboxy terminal domain of colicin E5 complexed with its inhibitor | Escherichia coli |
2EJF | 2 | Biotin Protein Ligase (Mutations R48A and K111A) and Biotin Carboxyl Carrier Protein Complex | Pyrococcus horikoshii |
2ES4 | 1.85 | Lipase-specific foldase in complex with its cognate lipase | Burkholderia glumae |
2FCW | 1.26 | LDL Receptor Ligand-Binding Modules 3–4 and the Receptor Associated Protein (RAP). | Homo sapiens |
2HQS | 1.5 | TolB/Pal complex | Escherichia coli |
2J9U | 2 | ESCRT-I Vps28 C-terminus in complex with the NZF-N domain from ESCRT-II | Saccharomyces cerevisiae |
2UUY | 1.15 | Structure of a tick tryptase inhibitor in complex with bovine trypsin | Bos taurus |
2UYZ | 1.4 | Non-covalent complex between Ubc9 and SUMO1 | Homo sapiens |
2VN5 | 1.9 | Dockerin-cohesin complex | [Clostridium] cellulolyticum |
2WEL | 1.9 | SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin | Homo sapiens |
2XGY | 1.8 | Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A | Homo sapiens |
2Z0D | 1.9 | Human Atg4B- LC3(1–120) complex | Homo sapiens |
3A8I | 1.99 | Crystal Structure of ET-EHred-5-CH3-THF complex | Escherichia coli |
3EGV | 1.75 | Ribosomal protein L11 methyltransferase (PrmA) in complex with trimethylated ribosomal protein L11 | Thermus thermophilus |
3K2M | 1.75 | Monobody HA4/Abl1 SH2 Domain Complex | Homo sapiens |
3MN5 | 1.5 | Actin-bound WH2 domains of Spire | Drosophila melanogaster |
4CJ2 | 1.5 | HEWL in complex with affitin H4 | Gallus gallus |
4DEX | 2 | Voltage Dependent Calcium Channel beta-2 Subunit in Complex With The CaV2.2 I-II Linker. | Oryctolagus cuniculus |
4M3K | 1.48 | Single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase | Bacillus licheniformis |
4MRT | 2 | Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | Bacillus subtilis |
4Q57 | 1.8 | plectin 1a actin-binding domain/N-terminal domain of calmodulin complex | Homo sapiens |