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Table 1 Transient protein-protein complexes of known 3-D structure employed for the analysis. For every entry in this dataset, a corresponding PDB entry is observed in the ‘unbound’ for at least one of the two proteins in the complex (details are in Additional file 1: Table S1)

From: Interface residues of transient protein-protein complexes have extensive intra-protein interactions apart from inter-protein interactions

PDB code Resolution (Å) Complex structure title Source organism
1AY7 1.7 Ribonuclease SA complex with Barstar Bacillus amyloliquefaciens
1B0N 1.9 SINR/SINI protein complex Bacillus subtilis
1F3V 2 N-terminal domain of TRADD and the TRAF domain of TRAF2 Homo sapiens
1FM0 1.45 Molybdopterin Synthase (MOAD/MOAE) Escherichia coli
1G73 2 SMAC bound to XIAP-BIR3 domain Homo sapiens
1GL4 2 Nidogen-1 G2/Perlecan IG3 Complex Mus musculus
1HX1 1.9 BAG domain in complex with the HSC70 ATPASE domain Bos taurus
1JIW 1.74 APR-APRin complex Pseudomonas aeruginosa
1NRJ 1.7 Signal Recognition Particle Receptor Beta-Subunit in Complex with the SRX Domain from the Alpha-Subunit Saccharomyces cerevisiae
1O6S 1.8 Internalin (Listeria monocytogenes) / E-Cadherin (human) Recognition Complex Homo sapiens
1OR7 2 Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA Escherichia coli
1PXV 1.8 Staphostatin-staphopain complex Staphylococcus aureus
1R0R 1.1 Protein Inhibitor, OMTKY3, and the Serine Protease, Subtilisin Carlsberg Bacillus licheniformis
1T0F 1.85 TnsA/TnsC(504–555) complex Escherichia coli
1T6G 1.8 Triticum aestivum xylanase inhibitor-I in complex with aspergillus niger xylanase-I Aspergillus niger
1TA3 1.7 Crystal Structure of xylanase (GH10) in complex with inhibitor (XIP) Aspergillus nidulans
1WQJ 1.6 Insulin-Like Growth Factors (IGFs) in complex with IGF Binding Proteins (IGFBPs) Homo sapiens
1Z0J 1.32 Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5 Homo sapiens
1Z5Y 1.94 N-Terminal Domain Of The Electron Transfer Catalyst DsbD and The Cytochrome c Biogenesis Protein CcmG Escherichia coli
1ZHH 1.94 Apo Form of Vibrio Harveyi LUXP Complexed with the Periplasmic Domain of LUXQ Vibrio harveyi
1ZLH 1.7 Crystal structure of the tick carboxypeptidase inhibitor in complex with bovine carboxypeptidase A Bos taurus
2APO 1.95 Methanococcus jannaschii Cbf5 Nop10 Complex Methanocaldococcus jannaschii
2CIO 1.5 Papain complexed with fragments of the Trypanosoma brucei cysteine protease inhibitor ICP. Carica papaya
2DFX 1.9 Carboxy terminal domain of colicin E5 complexed with its inhibitor Escherichia coli
2EJF 2 Biotin Protein Ligase (Mutations R48A and K111A) and Biotin Carboxyl Carrier Protein Complex Pyrococcus horikoshii
2ES4 1.85 Lipase-specific foldase in complex with its cognate lipase Burkholderia glumae
2FCW 1.26 LDL Receptor Ligand-Binding Modules 3–4 and the Receptor Associated Protein (RAP). Homo sapiens
2HQS 1.5 TolB/Pal complex Escherichia coli
2J9U 2 ESCRT-I Vps28 C-terminus in complex with the NZF-N domain from ESCRT-II Saccharomyces cerevisiae
2UUY 1.15 Structure of a tick tryptase inhibitor in complex with bovine trypsin Bos taurus
2UYZ 1.4 Non-covalent complex between Ubc9 and SUMO1 Homo sapiens
2VN5 1.9 Dockerin-cohesin complex [Clostridium] cellulolyticum
2WEL 1.9 SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin Homo sapiens
2XGY 1.8 Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A Homo sapiens
2Z0D 1.9 Human Atg4B- LC3(1–120) complex Homo sapiens
3A8I 1.99 Crystal Structure of ET-EHred-5-CH3-THF complex Escherichia coli
3EGV 1.75 Ribosomal protein L11 methyltransferase (PrmA) in complex with trimethylated ribosomal protein L11 Thermus thermophilus
3K2M 1.75 Monobody HA4/Abl1 SH2 Domain Complex Homo sapiens
3MN5 1.5 Actin-bound WH2 domains of Spire Drosophila melanogaster
4CJ2 1.5 HEWL in complex with affitin H4 Gallus gallus
4DEX 2 Voltage Dependent Calcium Channel beta-2 Subunit in Complex With The CaV2.2 I-II Linker. Oryctolagus cuniculus
4M3K 1.48 Single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase Bacillus licheniformis
4MRT 2 Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein Bacillus subtilis
4Q57 1.8 plectin 1a actin-binding domain/N-terminal domain of calmodulin complex Homo sapiens