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Table 8 Synergies between data sets

From: Integration of multiple types of genetic markers for neuroblastoma may contribute to improved prediction of the overall survival

Data set MA-145  
  OOB Cross-validation
Feature set MA50 CNV MA+CNV Syn. MA50 CNV MA+CNV Syn.
Stage 2         
T-test 0.693 0.537 0.693 -0.001 0.709 0.546 0.698 -0.011
IG-1D 0.729 0.617 0.755 0.026 0.737 0.632 0.765 0.028
IG-2D 0.721 0.484 0.740 0.019 0.731 0.493 0.750 0.020
T-test + lasso 0.808 0.536 0.804 -0.004 0.831 0.553 0.827 -0.004
Stage 3         
T-test 0.714 0.479 0.717 0.004 0.647 0.192 0.632 -0.015
IG-1D 0.747 0.583 0.764 0.017 0.661 0.258 0.662 0.001
IG-2D 0.730 0.514 0.740 0.010 0.655 0.308 0.656 0.000
T-test+lasso 0.808 0.506 0.825 0.017 0.648 0.194 0.652 0.005
  G-145  
  OOB     cross-validation    
Feature set G50 CNV G+CNV Syn. G50 CNV G+CNV Syn.
Stage 2         
T-test 0.714 0.537 0.720 0.006 0.716 0.546 0.725 0.009
IG-1D 0.766 0.617 0.780 0.014 0.778 0.632 0.786 0.009
IG-2D 0.743 0.484 0.747 0.004 0.756 0.493 0.757 0.001
T-test+lasso 0.848 0.536 0.853 0.005 0.865 0.553 0.868 0.003
Stage 3         
T-test 0.714 0.478 0.730 0.016 0.650 0.192 0.640 -0.011
IG-1D 0.747 0.582 0.786 0.039 0.661 0.258 0.662 0.001
IG-2D 0.730 0.511 0.767 0.037 0.650 0.308 0.650 0.000
T-test+lasso 0.808 0.506 0.858 0.050 0.655 0.194 0.655 0.000
  1. Synergies between data sets displayed for two stages of the analysis for MA+CNV and G+CNV data sets. MA50 and G50 are sets MA-145 and G-145 data sets limited to top 50 variables, respectively. Cases, for which MCC for mixed model is higher then either of the components, suggesting possible synergy are highlighted in boldface