Biology Direct

Table 1 Number of differentially expressed genes (DEG) with and without domains for considered datasets and mappers

From: Genes sharing the protein family domain decrease the performance of classification with RNA-seq genomic signatures

Mapers	No of DEG	Datasets
		GSE22260	GSE50760	GSE87340
Hisat	Total	359	7182	11048
	With/no domains	245 / 114	5141 / 2041	7839 / 3209
Star	Total	430	7264	11619
	With/no domains	271 / 159	5165 / 2055	7985 / 3634
Subread	Total	579	7918	11402
	With/no domains	369 / 210	5350 / 2568	8029 / 3373

For each dataset and mapper the number of total number of DEG, as well as number of DEG with and without domains was calculated. In each case there were more DEG with domains

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ISSN: 1745-6150

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