Fig. 5
Comparison of the ratio of disseminated cells rdiss between simulation scenarios. a The plot shows the ratio of disseminated cells [Eq. (3)] over time for all scenarios. The disseminated cell ratio increases linearly over time for all scenarios and γ-values. b The plot shows the maximum value of the disseminated cell ratio rdiss [Eq. (3)] in percent as a function of the adhesion heterogeneity parameter γ. The maximum of rdiss significantly (p<0.001) increases with higher γ-values for all scenarios with γ>0. For fixed γ-values the difference between scenarios III and IV (α=0, CONTROL −) and scenarios I and II (α=1, CONTROL +) is significant for all γ (p<0.05). See Additional file 4 for full statistics. Colours of data points are in accordance with scenario colours in Fig. 3