TY - JOUR AU - Iwakiri, Junichi AU - Terai, Goro AU - Hamada, Michiaki PY - 2017 DA - 2017/06/08 TI - Computational prediction of lncRNA-mRNA interactions by integrating tissue specificity in human transcriptome JO - Biology Direct SP - 15 VL - 12 IS - 1 AB - Long noncoding RNAs (lncRNAs) play a key role in normal tissue differentiation and cancer development through their tissue-specific expression in the human transcriptome. Recent investigations of macromolecular interactions have shown that tissue-specific lncRNAs form base-pairing interactions with various mRNAs associated with tissue-differentiation, suggesting that tissue specificity is an important factor controlling human lncRNA-mRNA interactions. SN - 1745-6150 UR - https://doi.org/10.1186/s13062-017-0183-4 DO - 10.1186/s13062-017-0183-4 ID - Iwakiri2017 ER -