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Table 1 Some quantitative properties of the map from RNA sequences to secondary structures at two different temperatures

From: Adaptive multiscapes: an up-to-date metaphor to visualize molecular adaptation

Phenotype Size at 37 °C Size at 43 °C \(p_{\text {stay}}^{37}\) \(p_{\text {stay}}^{43}\) \(p_{\text {stay}}^{37 \to 43}\) \(p_{\text {stay}}^{43 \to 37}\)
(((...))). 6935 4307 0.3961 0.3872 0.6209 0.9998
(((....))) 7791 5149 0.3864 0.3658 0.6585 0.9963
((....)).. 7766 5879 0.5142 0.4915 0.7550 0.9973
((.....)). 4802 2692 0.4431 0.4137 0.5539 0.9881
((......)) 1438 1 0.4092 0 0.0007 1
.(((...))) 2287 1542 0.3843 0.3661 0.6707 0.9948
.((....)). 5718 3624 0.4470 0.3996 0.6338 1
.((.....)) 944 0 0.3684 – 0 –
..((....)) 1729 360 0.3861 0.2928 0.2076 0.9972
  1. The non-empty phenotypes are listed in the first column, while the second and the third columns yield the size of the phenotype
  2. in two different environments (at two different folding temperatures, 37 °C and 43 °C); \(p_{\text {stay}}^{37}\) and \(p_{\text {stay}}^{43}\) are the probabilities that
  3. a point mutation does not change the phenotype at 37 °C or 43 °C, respectively; \(p_{\text {stay}}^{37 \to 43}\) is the probability that a given sequence
  4. folds in the same phenotype when the temperature changes from 37 °C to 43 °C, and similarly for \(p_{\text {stay}}^{43 \to 37}\)
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Biology Direct

ISSN: 1745-6150

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