Skip to main content


Fig. 4 | Biology Direct

Fig. 4

From: Adaptive multiscapes: an up-to-date metaphor to visualize molecular adaptation

Fig. 4

Multiscape of RNA sequences of length 10 folded at two different temperatures. There are 9 non-empty phenotypes at 37 °C and 8 at 43 °C, one of them having size 1. Fitness has been chosen to be proportional to the number of unpaired nucleotides in the hairpin loop, colors indicating fitness follow the coding scale introduced in previous figures. Thick solid lines between phenotypes in an environment represent a probability of changing phenotype under a point mutation above 5%; thin solid lines stand for probabilities between 1.5 and 5%; dashed grey lines are for probabilities between 1 and 1.5%; lower probabilities exist but are not shown for clarity. The largest promiscuity occurs between the same phenotype in the two environments (see Table 1); thick dashed light-blue lines indicate likely promiscuous transitions. Phenotypes are labeled in the 37 °C environment; they occupy the same position at 43 °C

Back to article page