Skip to main content

Advertisement

Table 1 The four genes analyzed in this study

From: Identification of positive selection in genes is greatly improved by using experimentally informed site-specific models

Gene # of residues Deep mutational scanning Alignment details
Yeast Gal4 DNA binding domain 64 [31] 17 sequences with 87% and 59% avg and min pairwise protein identity
β-lactamase 263 [14] 85 sequences with 82% and 63% avg and min pairwise protein identity
Influenza nucleoprotein (NP) 498 [32] 180 sequences with 95% and 90% avg and min pairwise protein identity
Influenza H1 hemagglutinin (HA) 564 [33] 111 sequences with 95% and 87% avg and min pairwise protein identity