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Fig. 1 | Biology Direct

Fig. 1

From: Emergence of heterogeneity in acute leukemias

Fig. 1

Examples of the clonal architecture detected in leukemic patients. Each tree corresponds to one patient. The cell at the top corresponds to the leukemic founder cell which acquires additional mutations and gives rise to multiple leukemic clones. The examples are taken from [12]. Reconstruction of the clonal architecture from genetic measurements is not always unique. In case of ambiguity only one possibility is shown in the figure

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