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Table 3 Selected pathways and genes on MS data

From: Weighted-SAMGSR: combining significance analysis of microarray-gene set reduction algorithm with pathway topology-based weights to select relevant genes

  Pathways with high frequency (frequency %) Genes (frequency %)
SAMGSR DNA Directed DNA Polymease Activity (100 %) POLD4 (100 %) POLD1 (80 %)
DNA Polymease Activity (90 %) PHB (80 %) GPAA1 (70 %)
COVALENT_CHROMATIN_MODIFICATION (70 %) PIGT (70 %) DPM3 (70 %)
HISTONE_MODIFICATION (70 %) MRE11A (60 %) PI4KB (60 %)
Stability = 14.04 % Stability = 12.83 %
Weighted-SAMGSR DNA_RECOMBINATION (70 %) LIPOPROTEIN_BIOSYNTHETIC_PROCESS (70 %) MRE11A (90 %) PTPRC (80 %)
NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS (70 %) BRCA1 (70 %) ATM (70 %)
PROTEIN_AMINO_ACID_LIPIDATION (70 %) CHAF1A (70 %) PIGT (70 %)
DEPHOSPHORYLATION (60 %) INOSITOL_OR_PHOSPHATIDYLINOSITOL_KINASE_ACTIVITY (60 %) GPAA1 (70 %) PI4KB (70 %)
LIPOPROTEIN_METABOLIC_PROCESS (60 %) PROTEIN_C_TERMINUS_BINDING (60 %) PEX16 (60 %) POLD1 (60 %)
POLD4 (60 %) PPP1CA (60 %)
Stability = 15.76 % Stability = 14.03 %  
  1. Note: Gene symbols in bold are those overlapped genes by SAMGSR and weighted-SAMGSR; gene symbols underlined are directly related to MS according to the genecards database