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Table 1 ROC-AUC and PR-AUC values for 43 Human PDZ domains with real negative interaction data

From: modPDZpep: a web resource for structure based analysis of human PDZ-mediated interaction networks

Domain ROC-AUC PR-AUC #Binder #Non-binder
DLG4_1 0.53 0.52 71 5
DLG4_3 0.74 0.76 89 5
ErbinLAP2 0.79 0.84 43 13
GIPC1_TIP_2 0.64 0.60 26 13
GOPC 0.32 0.34 13 8
GRIP2_2 0.47 0.69 6 5
GRIP2_3 0.78 0.82 8 5
InaDl_1 0.66 0.74 48 7
InaDl_2 0.80 0.86 53 7
InaDl_3 0.71 0.74 67 7
InaDl_4 0.68 0.75 40 7
InaDl_5 0.67 0.64 43 7
InaDl_6 0.60 0.58 41 6
InaDl_7 0.56 0.54 36 7
InaDl_8 0.45 0.52 30 6
InaDl_9 0.43 0.52 31 7
LIN7B 0.14 0.31 11 6
MAGI1_3 0.86 0.86 53 27
MAGI1_5 0.75 0.70 14 30
MAGI2_1 0.84 0.86 22 10
MAGI2_4 0.68 0.78 21 15
MAGI2_5 0.68 0.73 20 16
MAGI2_6 0.77 0.79 21 9
MAGI3_1 0.68 0.64 11 12
MAGI3_2 0.78 0.82 11 9
MAGI3_3 0.77 0.82 19 11
MAGI3_4 0.90 0.93 30 12
MUPP1_10 0.69 0.68 39 5
MUPP1_11 0.78 0.83 18 8
MUPP1_12 0.81 0.81 25 8
MUPP1_13 0.86 0.86 42 6
MUPP1_1 0.97 0.98 79 5
MUPP1_2 0.93 0.94 53 5
MUPP1_3 0.94 0.95 53 5
MUPP1_4 0.93 0.95 19 5
MUPP1_5 0.94 0.96 37 5
MUPP1_6 0.8 0.88 12 5
MUPP1_7 0.94 0.96 32 5
MUPP1_8 0.85 0.85 18 6
MUPP1_9 0.93 0.95 37 6
PICK1 0.51 0.56 36 6
PTPN13_PTPL1_PTP1E_1 0.53 0.62 15 5
PTPN13_PTPL1_PTP1E_2 0.63 0.64 35 8
Average 0.71 0.75 - -
  1. In cases where number of non-binders was much less compared to the number of binders, AUC was calculated by dividing the binders into multiple sets such that, approximately equal number of binder and non-binder were in each set and average AUC values are reported