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Fig. 8 | Biology Direct

Fig. 8

From: Primary and metastatic tumor dormancy as a result of population heterogeneity

Fig. 8

Allee growth model with distributed parameter m (m-distributed Allee model). The initial distribution is truncated exponential on the interval m [0, 1], with parameter of the distribution being μ = 100. Other parameters are c = 1, l = 1; the initial population size is N(0) = 0.2. a Total population size N(t) decreases in the months and years preceding the escape phase. b The expected value of m increases during the escape phase, (c) as does variance of m. However, Var t[m] decreases dramatically at an equilibrium state. d Distribution of clones also changes noticeably over time, selecting for clones with higher values of m

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