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Fig. 3 | Biology Direct

Fig. 3

From: Estimation of ribosome profiling performance and reproducibility at various levels of resolution

Fig. 3

Comparison of position-specific occupancies. a Two measured profiles for the S. cerevisiae gene YMR272C from replicates in the Ingolia-2009 dataset [10]. Bars represent the approximated location of the A-site (15 nt downstream from the 5’ end of the measured read). The average coverage in this profile is 8.4 % (7.4 % in the first replicate and 9.5 % in the second one). This is the 3rd quartile transcript according to coverage in this dataset (its coverage is higher than that of 75 % of the genes). b Scatter plot of the respective read counts in all nucleotide positions, in each of the replicates for the transcript in panel (a). Spearman’s rho, p-value and the number of points are denoted above the plot. c The median per-position correlation between all pairs of replicates for all genes and for the subset of 20 % highly expressed genes in each dataset

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