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Fig. 4 | Biology Direct

Fig. 4

From: Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antivirals

Fig. 4

Inhibitory small molecules identified using the CFPS have an inhibitory effect in live virus assay. a Various compounds demonstrated a dose-dependent inhibition of RVFV NP assembly in the plate assay. b Similar compounds were effective against LASV NP assembly. c The selected “hit” compounds were potent in the live virus assay for both RVFV and LASV. d Exposure of the compounds to HEK-293 cells indicates no toxicity in their active concentration

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