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Table 1 Summary of identified SiMPRes. Regions are grouped according to their significance level (see Methods) and their dominant mutation type

From: Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development

  Dominant mutation type
Missense mutations Insertions Deletions Total
Significance level High significance 68 5 10 83 (15.5 %)
Medium significance 77 0 13 90 (16.9 %)
Low significance 285 9 67 361 (67.6 %)
TOTAL 430 (80.5 %) 14 (2.6 %) 90 (16.9 %) 534 (100 %)