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Table 1 Summary of identified SiMPRes. Regions are grouped according to their significance level (see Methods) and their dominant mutation type

From: Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development

 

Dominant mutation type

Missense mutations

Insertions

Deletions

Total

Significance level

High significance

68

5

10

83 (15.5 %)

Medium significance

77

0

13

90 (16.9 %)

Low significance

285

9

67

361 (67.6 %)

TOTAL

430 (80.5 %)

14 (2.6 %)

90 (16.9 %)

534 (100 %)