Fig. 4

Overlap between cancer-related genes and significantly mutated regions. Blue bars show proteins that harbor at least one region annotated to the correct cancer-type. Shades of blue show the significance level of the most significant region found. Grey bars show the number of proteins that harbor at least one region but where the region is annotated to a different cancer type. Red bars show the number of proteins without significant regions. Numbers above the bars show the number of mutations in the COSMIC database annotated to the cancer type. Order of cancer types reflects the decreasing number of known genes from left to right