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Table 7 Normalized root-mean-square error calculated for each experimental dataset utilized in the context of model fitting

From: Numerical simulation of vascular tumour growth under antiangiogenic treatment: addressing the paradigm of single-agent bevacizumab therapy with the use of experimental data

Cell line Reference Experimental group Range of experimental values RMSE NRMSE
KPL-4 (Bevacizumab monotherapy study) [60] Control 500.25 10.76 2.15 %
Treatment 83.23 7.00 8.41 %
(5 mg/kg)
KPL-4 (Bevacizumab combination treatment study) [60] Control 639.84 13.31 2.08 %
Treatment 165.70 11.77 7.10 %
(5 mg/kg)
H226 [61] Control 603.07 16.73 2.77 %
Treatment 1 241.23 22.22 9.21 %
(1 mg/kg)
Treatment 2 177.17 8.09 4.57 %
(5 mg/kg)
Treatment 3 76.32 21.17 27.74 %
(25 mg/kg)
HSCC1 [61] Control 504.05 10.27 2.04 %
Treatment 1 188.87 27.80 14.72 %
(1 mg/kg)
Treatment 2 164.08 27.87 16.99 %
(5 mg/kg)
Treatment 3 125.12 9.71 7.76 %
(25 mg/kg)
HCT116 [62] Control 2902.71 121.76 4.19 %
Treatment 1411.98 74.85 5.30 %
(15 mg/kg)
HCP40 [62] Control 2992.56 47.88 1.60 %
Treatment 178.66 9.31 5.21 %
(15 mg/kg)
HT29 [62] Control 2381.34 58.17 2.44 %
Treatment 1276.84 129.88 10.17 %
(15 mg/kg)
HP40 [62] Control 2484.60 100.50 4.04 %
Treatment 1454.25 93.24 6.41 %
(15 mg/kg)