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Table 2 Effect of the variation of one input parameter value at a time, on the value of the tumour plateau as well as on the timepoint of its attainment

From: Numerical simulation of vascular tumour growth under antiangiogenic treatment: addressing the paradigm of single-agent bevacizumab therapy with the use of experimental data

Parameter values Units Time of plateau (day) Value of plateau (mm3) Variation of plateau value (%)
λ 1 Reference value 0.192 day−1 95 17347 n/a
+20 % 0.2304 79 17347 0
−20 % 0.1536 118 17347 0
c Reference value 5.85 day−1 95 17347 n/a
+20 % 7.02 96 22803 +31.45 %
−20 % 4.68 101 12413 −28.44 %
d Reference value 0.00873 day−1 · mm−2 95 17347 n/a
+20 % 0.010476 87 13196 −23.93 %
−20 % 0.006984 99 24243 +39.75 %
  1. All results regarding variation of plateau value are in agreement with the respective calculations based on Eq. (9)