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Fig. 5 | Biology Direct

Fig. 5

From: Numerical simulation of vascular tumour growth under antiangiogenic treatment: addressing the paradigm of single-agent bevacizumab therapy with the use of experimental data

Fig. 5

Free growth pattern versus treated tumour growth pattern. a Simulation results for a tumour treated with bevacizumab according to a scheme used in the context of various in vivo experiments in mice [60, 61, 65] and characterized by the parameter values shown in Table 1 for an extended simulation time duration (150 days). b The time course of bevacizumab concentration in plasma for the simulated treatment scheme, the details of which are shown in Table 1. Values of parameters involved in the pharmacokinetic model for the case of host-mouse were extracted from [64]

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