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Fig. 4 | Biology Direct

Fig. 4

From: Numerical simulation of vascular tumour growth under antiangiogenic treatment: addressing the paradigm of single-agent bevacizumab therapy with the use of experimental data

Fig. 4

The growth pattern for a treated tumour and bevacizumab concentration timecourse in host’s plasma. a Simulation results for a tumour treated with bevacizumab. The regimen applied has been used in the context of various in vivo experiments in mice [60, 61, 65]. Parameter values are shown in Table 1. b The timecourse of bevacizumab concentration in plasma for the simulated treatment scheme, the details of which are shown in Table 1. Values of parameters involved in the pharmacokinetic model for the case of host-mouse were extracted from [64]

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