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Fig. 1 | Biology Direct

Fig. 1

From: Numerical simulation of vascular tumour growth under antiangiogenic treatment: addressing the paradigm of single-agent bevacizumab therapy with the use of experimental data

Fig. 1

Schematic representation of the two – compartmental pharmacokinetic model. k a absorption rate constant for the case of intravenous route of administration (intravenous infusion); V c , volume of central compartment; V out , volume of distribution of outer compartment; k 12 , distribution rate constant from central compartment to outer compartment; k 21 , distribution rate constant from outer compartment to central compartment; k e , elimination rate constant

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