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Table 1 Prebiotic physicochemical group genetic codea

From: The progene hypothesis: the nucleoprotein world and how life began

2nd 2nd nucleotide T C A G
Codons GTG GCG CAC CGC
ACG   TGC
GCA   CGT
Amino acids Hydrophobic nonpolar Small polar and nonpolar Dicarbonic Hydroxy
Val, n-Val, Leu, n-Leu, Ile, a-But Ala, Gly [Ser, Asp] Asp, Glu Ser [Thr]
  1. aIf diaminopurine nucleotide (A*) was used for the progene formation instead of adenine nucleotide (A), four codons will be in each column (see Consequences 2 and 3): PuTPu, PuCPu, PyA*Py, PyGPy where Pu—purine (A* or G), Py—pyrimidine (T, U or C)