Fig. 1
From: The progene hypothesis: the nucleoprotein world and how life began
The mechanism of the progene formation. 1—dinucleotide; 2—aminoacyl nucleotide; 3—amino acid; 4–3′ “tail”(p ~ pX ~ Aa, see text); 5—complementary H-bonds between “triplets”; 6—phosphodiesther bond; 7—stacking between nucleotides; 8—progene. a Formation of a unstable “triplet” between a dinucleotide (DN) and a aminoacyl nucleotide (AAN) due to stacking and specific interaction between the amino acid (Aa) and DN. b Formation of complementary interaction between two unstable “triplets”; the condition for formation of the template-directed phosphodiesther bond (PDEB) takes place between 2nd and 3d (amino acyl) nucleotides. c The progene; arises on B-stage after PDEB formation between the DN and the AAN; contains the nucleotide triplet, Aa specific for the DN and two macroerges (NpNpNp ~ pX ~ Aa)