Fig. 1From: Bacterial calpains and the evolution of the calpain (C2) family of peptidasesPhylogenetic tree for selected members of the calpain family. The tree generated by FastTree is shown. Coloured branches indicate significant bootstrap values where light green is 100Â %, dark green is >90Â %, brown is >85Â % and red >80Â %. Tips are labelled with UniProt identifiers (where possible). Coloured dots indicate classification, additional domains and non-peptidase homologues, where brown is Bacteria, green is a signal peptide, pink is a transmembrane region, red is a CIII domain, yellow is an EF-hand structure domain, blue is a zinc-finger domain, orange is a C2 domain, turquoise is another additional domain, and black is a non-peptidase homologue. For the key to sequences, see Additional file 4: Table S2Back to article page